nAChR agonist 2

• UNSPSC Description:

  nAChR agonist 2 (compound 8) is a selective alpha4beta2 (α4β2) nAChR agonist (Kd=26 nM)[1].

• Target Antigen:

  nAChR

• Type:

  Reference compound

• Related Pathways:

  Membrane Transporter/Ion Channel;Neuronal Signaling

• Applications:

  Neuroscience-Neuromodulation

• Field of Research:

  Neurological Disease

• Assay Protocol:

  https://www.medchemexpress.com/nachr-agonist-2.html

• Solubility:

  10 mM in DMSO

• Smiles:

  C[C@H](NC)C/C=C/C1=CC=CN=C1

• Molecular Weight:

  176.26

• References & Citations:

  [1]Huang X, et al. Modeling subtype-selective agonists binding with alpha4beta2 and alpha7 nicotinic acetylcholine receptors: effects of local binding and long-range electrostatic interactions. J Med Chem. 2006;49(26):7661-7674.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  252870-46-5