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NAChR agonist 2

CAT: 0804-HY-115764Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-115764Size:1 Each
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Description
NAChR agonist 2 (compound 8) is a selective alpha4beta2 (α4β2) nAChR agonist (Kd=26 nM) [1].
CAS Number
252870-46-5
UNSPSC
12352005
Target
NAChR
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/nachr-agonist-2.html
Solubility
10 mM in DMSO
Smiles
C[C@H](NC)C/C=C/C1=CC=CN=C1
Molecular Formula
C11H16N2
Molecular Weight
176.26
References & Citations
[1]Huang X, et al. Modeling subtype-selective agonists binding with alpha4beta2 and alpha7 nicotinic acetylcholine receptors: effects of local binding and long-range electrostatic interactions. J Med Chem. 2006;49 (26) :7661-7674.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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