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Val-Cit-PABC-DOX

CAT: 0804-HY-160774Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-160774Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Val-Cit-PABC-DOX (compound 10109), an epsilon-poly-L-lysine-based drug conjugate, is an agent-linker conjugate for ADC by using a DNA topoisomerase I and topoisomerase II inhibitor, Doxorubicin , linked via the linker, Val-Cit-PABC[1].
CAS Number
1022094-34-3
UNSPSC
12352203
Target
Drug-Linker Conjugates for ADC; Topoisomerase
Type
ADC Related
Related Pathways
Antibody-drug Conjugate/ADC Related; Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/val-cit-pabc-dox.html
Purity
95.06
Smiles
OC1=C(C(C2=CC=CC(OC)=C2C3=O)=O)C3=C(O)C4=C1C[C@](C(CO)=O)(O)C[C@@H]4O[C@H]5C[C@@H]([C@@H]([C@@H](O5)C)O)NC(OCC6=CC=C(C=C6)NC([C@H](CCCNC(N)=O)NC([C@@H](N)C(C)C)=O)=O)=O
Molecular Formula
C46H56N6O16
Molecular Weight
948.97
References & Citations
[1]Furao Zhang, et al. Epsilon-poly-l-lysine-based drug conjugate, intermediate thereof, and application thereof. WO2023078464A1.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, sealed storage, away from moisture and light)
Scientific Category
ADC Related
Clinical Information
No Development Reported
Isoform
Traditional Cytotoxic Agents

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