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(E/Z) -CP-724714

CAT: 0804-HY-W008914-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-W008914-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
(E/Z) -CP-724714 is a racemic compound of (E) -CP-724714 and (Z) -CP-724714 isomers. CP-724714 is a potent and selective orally active ErbB2 (HER2) inhibitor[1].
CAS Number
537705-08-1
UNSPSC
12352005
Target
EGFR
Type
Reference compound
Related Pathways
JAK/STAT Signaling; Protein Tyrosine Kinase/RTK
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/e-z-cp-724714.html
Solubility
10 mM in DMSO
Smiles
O=C(NC/C=C/C1=CC2=C(NC3=CC=C(OC4=CC=C(C)N=C4)C(C)=C3)N=CN=C2C=C1)COC
Molecular Formula
C27H27N5O3
Molecular Weight
469.53
References & Citations
[1]Jani JP, et al. Discovery and pharmacologic characterization of CP-724,714, a selective ErbB2 tyrosine kinase inhibitor. Cancer Res, 2007, 67 (20), 9887-9893.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
ErbB2/HER2

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