Lycopene

• Description:

  Lycopene is naturally occurring carotenoids found in tomato, tomato products, and in other red fruits and vegetables; exhibits antioxidant effects.

• UNSPSC:

  12352211

• Hazard Statement:

  H302, H315, H319, H335

• Target:

  Endogenous Metabolite; Reactive Oxygen Species (ROS)

• Type:

  Natural Products

• Related Pathways:

  Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Cardiovascular Disease; Cancer

• Assay Protocol:

  https://www.medchemexpress.com/Lycopene.html

• Purity:

  99.70

• Solubility:

  THF : 5 mg/mL (ultrasonic)

• Smiles:

  C/C (C) =C\CC/C (C) =C/C=C/C (C) =C/C=C/C (C) =C/C=C/C=C (/C=C/C=C (C) /C=C/C=C (CC/C=C (C) \C) \C) C

• Molecular Formula:

  C40H56

• Molecular Weight:

  536.87

• Precautions:

  H302, H315, H319, H335

• References & Citations:

  [1]Assar EA, et al. Lycopene acts through inhibition of IκB kinase to suppress NF-κB signaling in human prostate and breast cancer cells. Tumour Biol. 2016 Jul;37 (7) :9375-85.|[2]Tapiero H, et al. The role of carotenoids in the prevention of human pathologies. Biomed Pharmacother. 2004 Mar;58 (2) :100-10.|[3]Müller L, et al. Lycopene and Its Antioxidant Role in the Prevention of Cardiovascular Diseases-A Critical Review. Crit Rev Food Sci Nutr. 2016 Aug 17;56 (11) :1868-79.|[4]Abass MA, et al. Lycopene ameliorates atrazine-induced oxidative damage in adrenal cortex of male rats by activation of the Nrf2/HO-1 pathway. Environ Sci Pollut Res Int. 2016 Aug;23 (15) :15262-74.|[5]Bandeira AC, et al. Lycopene inhibits reactive oxygen species production in SK-Hep-1 cells and attenuates acetaminophen-induced liver injury in C57BL/6 mice. Chem Biol Interact. 2017 Feb 1;263:7-17.

• Shipping Conditions:

  Dry Ice

• Storage Conditions:

  -80°C, protect from light, stored under nitrogen

• Scientific Category:

  Natural Products

• Clinical Information:

  Phase 4

• Isoform:

  Human Endogenous Metabolite

• CAS Number:

  502-65-8