Lycorine methiodide

• Description :

  Lycorine methiodide (N-Methyllycorine iodide) is a derivative of Lycorine (HY-N0288) . Lycorine methiodide exhibits no significant in vitro antitumor activity against A549, OE21, Hs683, U373, SKMEL, and B16F10 cell lines, with all IC50 values greater than 10 μM[1].

• Product Name Alternative :

  N-Methyllycorine (iodide)

• UNSPSC :

  12352005

• Target :

  Drug Derivative

• Related Pathways :

  Others

• Field of Research :

  Cancer

• Smiles :

  C[N+]12[C@@]3([H])[C@]([C@@H]([C@H](C=C3CC2)O)O)([H])C4=CC(OCO5)=C5C=C4C1.[I-]

• Molecular Formula :

  C17H20INO4

• Molecular Weight :

  429.25

• References & Citations :

  [1]Lamoral-Theys D, et al. Lycorine, the main phenanthridine Amaryllidaceae alkaloid, exhibits significant antitumor activity in cancer cells that display resistance to proapoptotic stimuli: an investigation of structure-activity relationship and mechanistic insight. J Med Chem. 2009 Oct 22;52 (20) :6244-56.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [15069-99-5]