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CE120 rabbit pAb

CAT: 0855-ES17529-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0855-ES17529-01Size:50 µL
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Background
This gene encodes a protein that functions in the microtubule-dependent coupling of the nucleus and the centrosome. A similar protein in mouse plays a role in both interkinetic nuclear migration, which is a characteristic pattern of nuclear movement in neural progenitors, and in neural progenitor self-renewal. Mutations in this gene are predicted to result in neurogenic defects. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009]
Description
This gene encodes a protein that functions in the microtubule-dependent coupling of the nucleus and the centrosome. A similar protein in mouse plays a role in both interkinetic nuclear migration, which is a characteristic pattern of nuclear movement in neural progenitors, and in neural progenitor self-renewal. Mutations in this gene are predicted to result in neurogenic defects. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009],
UniProt
Q8N960
Swiss Prot
Q8N960
Reactivity
Human; Mouse
Immunogen
Synthesized peptide derived from human CE120 AA range: 335-385
Target
CE120
Clonality
Polyclonal
Source
Rabbit
Applications
WB
Concentration
1 mg/ml
Dilution
WB 1:500-2000
Buffer
-20°C/1 year
Storage Conditions
-20°C/1 year
Fragment
IgG
Subcellular Location
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Regulates the localization of TACC3 to the centrosome in neural progenitors in vivo. .
Gene ID (Human)
153241

UniProtKB · Q8N960

Centrosomal protein of 120 kDa

CE120_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q8N960
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
CEP120
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
Cep120
EC number
—
Processing
—
Secondary accessions
Q6AI52, Q6AW89, Q8IWB5, Q8N9Y0, Q8NDE8
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

Disease

CiliopathyDisease variantJoubert syndrome

Domain

Coiled coilRepeat

Cellular component

CytoplasmCytoskeleton

PTM

Phosphoprotein

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