Products for Research Use Only
RegisterLogin

S7A14 rabbit pAb

CAT: 0855-ES13220-01Size: 50 µLDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0855-ES13220-01Size:50 µL
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Background
This gene is predicted to encode a glycosylated, cationic amino acid transporter protein with 14 transmembrane domains. This gene is primarily expressed in skin fibroblasts, neural tissue, and primary endothelial cells and its protein is predicted to mediate lysosomal uptake of cationic amino acids. Mutations in this gene are associated with autosomal recessive retinitis pigmentosa. In mice, this gene is expressed in the photoreceptor layer of the retina where its expression increases over the course of retinal development and persists in the mature retina. [provided by RefSeq, Apr 2014]
Description
This gene is predicted to encode a glycosylated, cationic amino acid transporter protein with 14 transmembrane domains. This gene is primarily expressed in skin fibroblasts, neural tissue, and primary endothelial cells and its protein is predicted to mediate lysosomal uptake of cationic amino acids. Mutations in this gene are associated with autosomal recessive retinitis pigmentosa. In mice, this gene is expressed in the photoreceptor layer of the retina where its expression increases over the course of retinal development and persists in the mature retina. [provided by RefSeq, Apr 2014],
Product Name Alternative
Probable cationic amino acid transporter (Solute carrier family 7 member 14)
UniProt
Q8TBB6
Swiss Prot
Q8TBB6
Reactivity
Human; Mouse
Immunogen
Synthesized peptide derived from human S7A14 AA range: 50-100
Target
S7A14
Clonality
Polyclonal
Source
Rabbit
Applications
WB
Concentration
1 mg/ml
Dilution
WB 1:500-2000
Buffer
-20°C/1 year
Molecular Weight
85kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
85kD
Fragment
IgG
Subcellular Location
Lysosome membrane ; Multi-pass membrane protein . Exhibits a punctated pattern in the cytoplasm, which partially ovelaps with lysosomes.
Other Product Names
Probable cationic amino acid transporter (Solute carrier family 7 member 14)
Gene ID (Human)
57709

UniProtKB · Q8TBB6

Solute carrier family 7 member 14

S7A14_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q8TBB6
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
SLC7A14
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
B3KV33, Q9HCF9
Protein keywords

Biological process

Amino-acid transportTransport

PTM

GlycoproteinPhosphoprotein

Cellular component

LysosomeMembrane

Technical term

Proteomics identificationReference proteome

Disease

Retinitis pigmentosa

Domain

TransmembraneTransmembrane helix

Related Products

CatalogName
ES13221-01S7A13 rabbit pAb
ES4666-01RAB3IP rabbit pAb
ES20659-01NBR1 Rabbit rabbit pAb
ES20825-01ATG7 Rabbit rabbit pAb
ES20831-01ATG13 Rabbit rabbit pAb
ES20599-01VEGF Rabbit rabbit pAb
ES20596-01WIPI2 Rabbit rabbit pAb
ES20751-01Gab1 Rabbit rabbit pAb
ES20703-01JAK2 Rabbit rabbit pAb
ES20758-01ERK1 Rabbit rabbit pAb

Alternative Products

CatalogName
RA34716-01S7A14 rabbit pAb
GTR18402081-01S7A14 rabbit pAb Antibody
JOT-AP04635-01S7A14 Rabbit Polyclonal Antibody
WP3748-01U-Blot® S7A14 rabbit pAb
PAV3563Rabbit Anti-S7A14/SLC7A14 Polyclonal Antibody
C46133-01S7A14 Antibody
RTR125Rabbit-to-Rabbit Blocking Reagent
AR05252FC-NRabbit IgG Rabbit Protein
NBP1-71681Rabbit Normal Rabbit Serum
AR05110PU-NRabbit IgM Rabbit Protein

Popular Products