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CPDT

CAT: 0804-HY-W975966-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-W975966-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
CPDT is an orally active and highly potent inducer of phase 2 enzymes and an activator of Nrf2. The activities of key phase 2 enzymes, including glutathione S-transferase, NAD (P) H:quinone:oxidoreductase 1 and glutamate cysteine synthetase, and levels of glutathione were elevated by CPDT in rat bladder in vivo and in cultured bladder cells in vitro[1][2].
CAS Number
14085-33-7
UNSPSC
12352005
Hazard Statement
H301-H412
Target
Keap1-Nrf2
Related Pathways
NF-κB
Field of Research
Neurological Disease
Smiles
S=C1SSC2=C1CCC2
Molecular Formula
C6H6S3
Molecular Weight
174.31
Precautions
P264-P270-P273-P330-P405-P501
References & Citations
[1]Xiao-Yun Liu, et al. Neuroprotective effect of CPDT on THA-induced cortical motor neuron death in an organotypic culture model. Brain Res Bull. 2010 Nov 20;83 (6) :345-50. |[2]Joseph D Paonessa, et al. 5,6-Dihydrocyclopenta[c][1,2]-dithiole-3 (4H) -thione is a promising cancer chemopreventive agent in the urinary bladder. Chem Biol Interact. 2009 Jun 15;180 (1) :119-26.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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