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3'-Deoxy-3'-fluorothymidine-d3

CAT: 0804-HY-W740364-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-W740364-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
3'-Deoxy-3'-fluorothymidine-d3 is the deuterium labeled Alovudine. Alovudine (3'-Fluoro-3'-deoxythymidine) is a mtDNA synthesis inhibitor and a marker of DNA synthesis. Alovudine is less susceptible to inflammatory changes than 18F-Fluorodeoxyglucose (FDG) and thus is a better biomarker in pancreatic cancer. Alovudine shows anti-orthopoxvirus and anti-leukemic activity[1][2][3][4][5][6].
CAS Number
1346523-18-9
UNSPSC
12352005
Target
DNA/RNA Synthesis; Isotope-Labeled Compounds; Orthopoxvirus
Related Pathways
Anti-infection; Cell Cycle/DNA Damage; Others
Field of Research
Cancer
Smiles
O=C1C(C([2H])([2H])[2H])=CN(C(N1)=O)[C@H]2C[C@@H]([C@H](O2)CO)F
Molecular Formula
C10H10D3FN2O4
Molecular Weight
247.24
Shipping Conditions
Room temperature
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported

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