4-Deoxy-3’-deoxy-3’-fluoro uridine

4-Deoxy-3’-deoxy-3’-fluoro uridine

• UNSPSC Description: 4-Deoxy-3’-deoxy-3’-fluoro uridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
• Target Antigen: Nucleoside Antimetabolite/Analog
• Type: Oligonucleotides
• Related Pathways: Cell Cycle/DNA Damage
• Applications: Cancer-programmed cell death
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/4-deoxy-3-deoxy-3-fluoro-uridine.html
• Solubility: 10 mM in DMSO
• Smiles: O=C1N=CC=CN1[C@H]2[C@H](O)[C@H](F)[C@@H](CO)O2
• Molecular Weight: 230.19
• References & Citations: [1]Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported