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3′-Deoxy-3′-iodothymidine

CAT: 0804-HY-154088Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-154088Size:1 Each
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Description
3′-Deoxy-3′-iodothymidine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
CAS Number
14260-82-3
UNSPSC
12352005
Target
Nucleoside Antimetabolite/Analog
Type
Oligonucleotides
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/3-deoxy-3-iodothymidine.html
Solubility
10 mM in DMSO
Smiles
OC[C@@H]1[C@@H](I)C[C@H](C2C(NC(C(C)=C2)=O)=O)O1
Molecular Formula
C11H14INO4
Molecular Weight
351.14
References & Citations
[1]Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18 (23) :3373-88.
Shipping Conditions
Room temperature
Scientific Category
Oligonucleotides
Clinical Information
No Development Reported

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