3′-Deoxy-3′-fluoroguanosine

3′-Deoxy-3′-fluoroguanosine

• CAS Number: 123402-21-1
• UNSPSC Description: 3′-Deoxy-3′-fluoroguanosine exhibits antiviral activity against tick-borne encephalitis virus (TBEV), through interaction with NS5B RdRp of HCV, resulting in suppression of viral RNA synthesis by disruption of further extension of the replicating viral RNA[1].
• Target Antigen: DNA/RNA Synthesis; HCV
• Type: Reference compound
• Related Pathways: Anti-infection;Cell Cycle/DNA Damage
• Applications: COVID-19-anti-virus
• Field of Research: Infection
• Assay Protocol: https://www.medchemexpress.com/3-deoxy-3-fluoroguanosine.html
• Purity: 99.29
• Solubility: DMSO : 20 mg/mL (ultrasonic)
• Smiles: NC(NC1=O)=NC2=C1N=CN2[C@@H]3O[C@H](CO)[C@@H](F)[C@H]3O
• Molecular Weight: 285.235
• References & Citations: [1]Eyer L, et al., Broad-Spectrum Antiviral Activity of 3'-Deoxy-3'-Fluoroadenosine against Emerging Flaviviruses. Antimicrob Agents Chemother. 2021 Jan 20;65(2):e01522-20.
• Shipping Conditions: Room Temperature
• Storage Conditions: 4°C (Powder, protect from light)
• Clinical Information: No Development Reported