2'-Fluorothymidine

• Product Name Alternative:

  2'-​Deoxy-​2'-​fluoro-​5-​Methyluridine

• UNSPSC Description:

  2'-Fluorothymidine (2'-Fluoro-2'-deoxythymidine), a bioisostere of both thymidine (TdR) and methyluridine, is a putative highly selective substrate for thymidine kinase type 2 (TK2)[1].

• Target Antigen:

  Others

• Type:

  Reference compound

• Related Pathways:

  Others

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/2-fluorothymidine.html

• Purity:

  99.07

• Solubility:

  DMSO : 125 mg/mL (ultrasonic)

• Smiles:

  OC[C@@H]1[C@@H](O)[C@@H](F)[C@H](N2C(NC(C(C)=C2)=O)=O)O1

• Molecular Weight:

  260.22

• References & Citations:

  [1]Wiebe LI, et al. Biochemistry and biology of 2'-Fluoro-2'-deoxythymidine (FT), a putative highly selective substrate for thymidine kinase type 2 (TK2). Curr Radiopharm. 2012 Jan;5(1):38-46.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  -20°C, 3 years; 4°C, 2 years (Powder)

• Clinical Information:

  No Development Reported

• CAS Number:

  122799-38-6