Nicotinamide N-oxide-d4

CAT: 0804-HY-W701397-01Size: 5 mgDry Ice: NoHazardous: No
CAT#:0804-HY-W701397-01Size:5 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Nicotinamide N-oxide-d4 is the deuterium labeled Nicotinamide N-oxide (HY-101407) . Nicotinamide N-oxide, an in vivo nicotinamide metabolite, is a potent, and selective antagonist of the CXCR2 receptor.
CAS Number
[1246817-64-0]
UNSPSC
12352005
Target
CXCR; Drug Metabolite; Endogenous Metabolite; Isotope-Labeled Compounds; Oxidative Phosphorylation
Related Pathways
GPCR/G Protein; Immunology/Inflammation; Metabolic Enzyme/Protease; Others
Field of Research
Inflammation/Immunology
Smiles
O=C(C1=C([2H])[N+]([O-])=C([2H])C([2H])=C1[2H])N
Molecular Formula
C6H2D4N2O2
Molecular Weight
142.15
References & Citations
[1]Real AM, et al. Nicotinamide N-oxidation by CYP2E1 in human liver microsomes. Drug Metab Dispos. 2013 Mar;41 (3) :550-3.|[2]Cutshall NS, et al. Nicotinamide N-oxides as CXCR2 antagonists. Bioorg Med Chem Lett. 2001 Jul 23;11 (14) :1951-4.
Shipping Conditions
Room temperature
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported

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