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Haloperidol-d4 N-Oxide

CAT: 0804-HY-14538S2-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-14538S2-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Haloperidol-d4 N-Oxide is the deuterium labeled Haloperidol. Haloperidol is a potent dopamine D2 receptor antagonist, widely used as an antipsychotic[1][2].
CAS Number
1246815-56-4
UNSPSC
12352005
Target
Dopamine Receptor; Isotope-Labeled Compounds
Type
Isotope-Labeled Compounds
Related Pathways
GPCR/G Protein; Neuronal Signaling; Others
Field of Research
Neurological Disease
Solubility
10 mM in DMSO
Smiles
OC1(CCN(CCCC(=O)C2=CC=C(F)C=C2)(=O)CC1)C3=C(C(=C(Cl)C(=C3[2H])[2H])[2H])[2H]
Molecular Formula
C21H19D4ClFNO3
Molecular Weight
395.89
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216. |[2]Shah NS, et al. Effects of chlorpromazine and haloperidol on the disposition of mescaline-14C in mice. J Pharmacol Exp Ther. 1973 Aug;186 (2) :297-304|[3]Furuta Y, et al. Effects of enzyme inhibitors of catecholamine metabolism and of haloperidol on the pancreatic secretion induced by L-DOPA and by dopamine in dogs. Br J Pharmacol. 1973 Jan;47 (1) :77-84
Shipping Conditions
Room temperature
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported
Isoform
D2 Receptor

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