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Nicotinamide-d4

CAT: 0804-HY-B0150S-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-B0150S-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Nicotinamide-d4 is the deuterium labeled Nicotinamide. Nicotinamide is a form of vitamin B3 that plays essential roles in cell physiology through facilitating NAD+ redox homeostasis and providing NAD+ as a substrate to a class of enzymes that catalyze non-redox reactions. Nicotinamide is an inhibitor of SIRT1.
CAS Number
347841-88-7
Product Name Alternative
Niacinamide-d4; Nicotinic acid amide-d4
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Endogenous Metabolite; Sirtuin
Type
Isotope-Labeled Compounds
Related Pathways
Cell Cycle/DNA Damage; Epigenetics; Metabolic Enzyme/Protease
Field of Research
Neurological Disease; Cancer
Purity
99.97
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
[2H]C1=C([2H])C([2H])=C(C(N)=O)C([2H])=N1
Molecular Formula
C6H2D4N2O
Molecular Weight
126.15
Precautions
H302, H315, H319, H335
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216. ; Bhansali SG, et al. Nicotinamide prevents apoptosis in human cortical neuronal cells. Toxicol Mech Methods. 2006;16 (4) :17|[2]Bhansali SG, et al. Nicotinamide prevents apoptosis in human cortical neuronal cells. Toxicol Mech Methods. 2006;16 (4) :173-80.|[3]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53 (2) :211-216.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported

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Alternative Products

CatalogName
AR-N08598-01Nicotinamide-d4
018096Nicotinamide-d4 (Major)
CS-O-51725Nicotinamide Riboside-D4
469744-01β-Nicotinamide-d4 Mononucleotide (d4-major)
TRC-N407768-10MGBeta-Nicotinamide-d4 Mononucleotide (d4-major)
TRC-N407762-50MGNicotinamide-d4 N-Oxide (d4 Major)
018098Nicotinamide-d4 N-Oxide
AR-N08586-01Nicotinamide Adenine Dinucleotide-d4
CS-O-44691Nicotinamide mononucleotide (NMN) -D4
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