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Succinate (calcium)

CAT: 0804-HY-W693142Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-W693142Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Succinate calcium is a key intermediate product of the citric acid cycle (tricarboxylic acid cycle) . Succinate calcium can act as a specific ligand for the G protein-coupled receptor GPR91. Succinate calcium can increase the amplitude of calcium transient in cardiac muscle cells and accelerate the decay rate of calcium transient. Succinate calcium can induce myocardial apoptosis[1].
CAS Number
140-99-8
UNSPSC
12352211
Hazard Statement
H302-H315-H319-H335
Target
Apoptosis; Orphan GPCR
Related Pathways
Apoptosis; GPCR/G Protein
Applications
Neuroscience-Neurodegeneration
Field of Research
Cardiovascular Disease
Smiles
O=C([O-])CCC([O-])=O.[Ca+2]
Molecular Formula
C4H4CaO4
Molecular Weight
156.15
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
References & Citations
[1]Aguiar C J, et al. Gomes E R M, et al. Succinate modulates Ca2+ transient and cardiomyocyte viability through PKA-dependent pathway[J]. Cell calcium, 2010, 47 (1) : 37-46.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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