NR2F6 modulator-2

• Description :

  NR2F6 modulator-2 (Compound I) is an autorepressed orphan nuclear receptor NR2F6 (Nuclear Receptor subfamily 2 group F member 6) modulator. NR2F6 modulator-2 can inhibits the recruitment of the bio-NSD1 peptide with an IC50 of 2.0 equivalents of NR2F6. NR2F6 modulator-2 can be used for the researches of cancer and immunology[1].

• UNSPSC :

  12352005

• Hazard Statement :

  H315-H319-H335

• Target :

  Orphan Nuclear Receptor

• Related Pathways :

  Vitamin D Related/Nuclear Receptor

• Applications :

  COVID-19-immunoregulation

• Field of Research :

  Cancer; Inflammation/Immunology

• Smiles :

  OC1=CC=C(NC(=O)C2=CC(=CC=C2Cl)[N+]([O-])=O)C=C1

• Molecular Formula :

  C13H9ClN2O4

• Molecular Weight :

  292.67

• Precautions :

  P261-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P362-P403+P233-P405-P501

• References & Citations :

  [1]Oerlemans GJM, et al. Structural Elucidation and Covalent Modulation of the Autorepressed Orphan Nuclear Receptor NR2F6. ACS Chem Biol. 2025 Sep 19;20 (9) :2308-2317.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [22978-55-8]