Trihexyl phosphate

• Description :

  Trihexyl phosphate is an organophosphate flame retardant. Trihexyl phosphate causes mitochondrial impairment and induces cell apoptosis in CHO cells. Trihexyl phosphate promotes the proliferation of human breast cancer cells (MCF-7) in a dose-dependent manner and exerts estrogenicity via ERα-independent pathways[1].

• UNSPSC :

  12352211

• Hazard Statement :

  H302, H315, H319, H335

• Target :

  Apoptosis

• Related Pathways :

  Apoptosis

• Field of Research :

  Cancer

• Purity :

  99.00

• Smiles :

  CCCCCCOP(=O)(OCCCCCC)OCCCCCC

• Molecular Formula :

  C18H39O4P

• Molecular Weight :

  350.47

• Precautions :

  H302, H315, H319, H335

• References & Citations :

  [1]Li Z, et al. Cytotoxic Screening and Transcriptomics Reveal Insights into the Molecular Mechanisms of Trihexyl Phosphate-Triggered Hepatotoxicity. Environ Sci Technol. 2020 Sep 15;54 (18) :11464-11475. |[2]Ji X, et al. In vitro estrogen-disrupting effects of organophosphate flame retardants. Sci Total Environ. 2020 Jul 20;727:138484.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  Store at room temperature 3 years

• Scientific Category :

  Reference compound2

• Clinical Information :

  No Development Reported

• CAS Number :

  [2528-39-4]