Platelet aggregation-IN-3

CAT: 0804-HY-176060Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-176060Size:1 Each
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Description
Platelet aggregation-IN-3 (Compound 5) is a ligand for H2 histamine receptors, α2 (A, C) -adrenergic receptors (α2-AR), and 5-HT2 (B, C) serotonin receptors. Platelet aggregation-IN-3 can inhibit platelet aggregation induced by ADP and collagen and can also modulate tumour cell-induced platelet aggregation (TCIPA) . Platelet aggregation-IN-3 is promising for research of antiplatelet therapy in cardiovascular diseases and the prevention of cancer-related thrombosis and tumour metastasis[1].
CAS Number
[1029802-21-8]
UNSPSC
12352005
Target
5-HT Receptor; Adrenergic Receptor; Histamine Receptor
Related Pathways
GPCR/G Protein; Immunology/Inflammation; Neuronal Signaling
Applications
Cancer-programmed cell death
Field of Research
Cancer; Cardiovascular Disease
Smiles
C1(NC2=CC=C3C(CCCC3)=C2)=NCCN1.Cl
Molecular Formula
C13H18ClN3
Molecular Weight
251.76
References & Citations
[1]Hante NK, et al. Effect of mono-guanidine-like derivatives on platelet aggregation and tumour cell induced platelet aggregation. RSC Med Chem. 2025 Jan 31;16 (4) :1695-1704.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
5-HT2 Receptor; H2 Receptor; Histamine Receptor; α adrenergic receptor

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