Thalidomide-O-PNB ester

• Description:

  Thalidomide-O-PNB ester is an E3 ubiquitin ligase cereblon (CRBN) ligand used to recruit the cereblon protein. Thalidomide-O-PNB ester can be linked to a target protein ligand via a linker to form a PROTAC.

• UNSPSC:

  12352005

• Target:

  Ligands for E3 Ligase

• Related Pathways:

  PROTAC

• Field of Research:

  Cancer

• Smiles:

  O=C1CCC(C(N1)=O)N2C(C3=C(C(OCC(OC4=CC=C([N+]([O-])=O)C=C4)=O)=CC=C3)C2=O)=O

• Molecular Formula:

  C21H15N3O9

• Molecular Weight:

  453.36

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• Isoform:

  Cereblon