PNB-001

• Description :

  PNB-001 is an orally active CCK2 selective ligand and antagonist. PNB-001 has anti-inflammatory and analgesic activities[1].

• UNSPSC :

  12352005

• Hazard Statement :

  H302, H315, H319

• Target :

  Cholecystokinin Receptor

• Type :

  Reference compound

• Related Pathways :

  GPCR/G Protein; Neuronal Signaling

• Applications :

  COVID-19-immunoregulation

• Field of Research :

  Inflammation/Immunology

• Assay Protocol :

  https://www.medchemexpress.com/pnb-001.html

• Purity :

  99.65

• Solubility :

  DMSO : 50 mg/mL (ultrasonic)

• Smiles :

  O=C1C=C(C(C2=CC=CC=C2)(N1CCC3=CC=CC=C3)O)Cl

• Molecular Formula :

  C18H16ClNO2

• Molecular Weight :

  313.78

• Precautions :

  H302, H315, H319

• References & Citations :

  [1]Lattmann E, et al. Cholecystokinin-2/gastrin antagonists: 5-hydroxy-5-aryl-pyrrol-2-ones as anti-inflammatory analgesics for the treatment of inflammatory bowel disease. Medchemcomm. 2017 Feb 17;8 (3) :680-685.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  4°C (Powder, protect from light)

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [1528760-09-9]