(2E) -TCO-PNB ester

• Description:

  (2E) -TCO-PNB ester is a Click Amino Acid that can be used as a linker in the synthesis of PROTAC molecules. (2E) -TCO-PNB ester contains a TCO group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing a Tetrazine group.

• UNSPSC:

  12352005

• Hazard Statement:

  H315, H319, H335

• Target:

  Biochemical Assay Reagents

• Related Pathways:

  Others

• Field of Research:

  Cancer

• Purity:

  99.69

• Solubility:

  DMSO : 100 mg/mL (ultrasonic)

• Smiles:

  O=C(OC1=CC=C([N+]([O-])=O)C=C1)OC2/C=C/CCCCC2

• Molecular Formula:

  C15H17NO5

• Molecular Weight:

  291.30

• Precautions:

  H315, H319, H335

• References & Citations:

  [1]Natasha Bidesi, et al. Synthesis and radiolabeling of a polar [125 I]I-1,2,4,5-tetrazine. J Labelled Comp Radiopharm. 2023 Jan;66 (1) :22-30.

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  -20°C, 3 years (Powder)

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  1580501-97-8