STAT6-IN-7

• Description:

  STAT6-IN-7 (Compound 178) is a STAT6 inhibitor. STAT6-IN-7 has an IC50 value for inhibiting the binding of human STAT6/pIL-4Rα of 0.28 μM. STAT6-IN-7 can be used in the research of inflammatory and allergic diseases[1].

• UNSPSC:

  12352005

• Hazard Statement:

  H302, H315, H319, H335

• Target:

  Interleukin Related; STAT

• Related Pathways:

  Immunology/Inflammation; JAK/STAT Signaling; Stem Cell/Wnt

• Field of Research:

  Inflammation/Immunology

• Purity:

  99.88

• Smiles:

  O=C(C1=CC(NC(C2=CC(C(F)(F)F)=CC3=C2N(CCOC)C(C4=CC=C(N5C(N(C)N=C5C)=O)C=C4)=C3)=O)=CC=C1)NC6=NN(C7CC7)C=C6

• Molecular Formula:

  C36H33F3N8O4

• Molecular Weight:

  698.69

• Precautions:

  H302, H315, H319, H335

• References & Citations:

  [1]YAMAMOTO, et al. Fused ring compound and pharmaceutical containing same. WO2024071439A1. 2024-04-04.

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  -20°C (Powder, protect from light, stored under nitrogen)

• Scientific Category:

  Reference compound2

• Clinical Information:

  No Development Reported

• Isoform:

  IL-4; STAT6

• CAS Number:

  [3033743-58-4]