STAT6-IN-5

• Description:

  STAT6-IN-5 (compound 84) is a STAT6 inhibitor (IC50=0.24 μM), which can be used for the research of inflammatory diseases and allergic diseases (e.g. atopic dermatitis) [1].

• UNSPSC:

  12352005

• Target:

  STAT

• Type:

  Reference compound

• Related Pathways:

  JAK/STAT Signaling; Stem Cell/Wnt

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Inflammation/Immunology

• Assay Protocol:

  https://www.medchemexpress.com/stat6-in-5.html

• Purity:

  99.88

• Solubility:

  DMSO : 100 mg/mL (ultrasonic)

• Smiles:

  O=C(C1=CC(C(F)(F)F)=CC2=C1N(CCOC)C(C3=CC=C(N4C(N(C)N=C4C)=O)C=C3)=C2)NC5=NN=C(C)S5

• Molecular Formula:

  C26H24F3N7O3S

• Molecular Weight:

  571.57

• References & Citations:

  [1]Fused ring compound and pharmaceutical containing the same. World Intellectual Property Organization, WO2024071439 A1 2024-04-04.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• Isoform:

  STAT6

• CAS Number:

  [3033742-22-9]