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GED 0507-34-Levo

CAT: 0804-HY-W109107Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-W109107Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
GED 0507-34-Levo is an orally active PPARγ modulator. GED 0507-34-Levo downregulates the expression of TGF-β, Smad3, IL-13, and CTGF in the colon. GED 0507-34-Levo improves DSS-induced chronic colitis and fibrosis[1].
CAS Number
921195-93-9
UNSPSC
12352005
Hazard Statement
H315-H319-H335
Target
Interleukin Related; PPAR; TGF-beta/Smad
Related Pathways
Cell Cycle/DNA Damage; Immunology/Inflammation; Metabolic Enzyme/Protease; Stem Cell/Wnt; TGF-beta/Smad; Vitamin D Related/Nuclear Receptor
Field of Research
Inflammation/Immunology
Smiles
O=C(O)[C@@H](OC)CC1=CC=C(N)C=C1
Molecular Formula
C10H13NO3
Molecular Weight
195.22
Precautions
P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501
References & Citations
[1]Speca S, et al. Novel PPARγ Modulator GED-0507-34 Levo Ameliorates Inflammation-driven Intestinal Fibrosis. Inflamm Bowel Dis. 2016 Feb;22 (2) :279-92.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
IL-13; PPARγ

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