Vasorelaxant agent-2

• Description:

  Vasorelaxant agent-2 (Compound 8h) targets α1A-adrenergic receptor with an affinity of pD2=5.4. Vasorelaxant agent-2 exhibits vasodilator activity in rats aortic rings with an EC50 of 0.79 μM[1].

• UNSPSC:

  12352005

• Hazard Statement:

  H302-H312-H315-H319-H332-H335

• Target:

  Adrenergic Receptor

• Related Pathways:

  GPCR/G Protein; Neuronal Signaling

• Field of Research:

  Cardiovascular Disease

• Smiles:

  O=C1NN=C(CC2=CC=C(Cl)C=C2)C3=C1C=CC=C3

• Molecular Formula:

  C15H11ClN2O

• Molecular Weight:

  270.71

• Precautions:

  P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

• References & Citations:

  [1]del Olmo E, et al., Vasorelaxant activity of phthalazinones and related compounds. Bioorg Med Chem Lett. 2006 May 15;16 (10) :2786-90.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  [53242-88-9]