CFL-137 (Standard)

• Description:

  CFL-137 is a potent KRasG12C inhibitor. CFL-137 shows an antiproliferative effect. CFL-137 shows anticancer activity. CFL-137 has the potential for the research of lung cancer[1].

• UNSPSC:

  12352005

• Target:

  Ras

• Related Pathways:

  GPCR/G Protein; MAPK/ERK Pathway

• Field of Research:

  Cancer

• Smiles:

  O=CC1=C2C=CC=CC2=CC=C1O

• Molecular Formula:

  C11H8O2

• Molecular Weight:

  172.18

• References & Citations:

  [1]Orgován Z, et al. Covalent fragment mapping of KRasG12C revealed novel chemotypes with in vivo potency. Eur J Med Chem. 2023 Mar 15;250:115212.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference Standards

• CAS Number:

  [708-06-5]