Anticancer agent 137

CAT: 0804-HY-155570Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-155570Size:1 Each
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Description
Anticancer agent 137 (8q) is a potent PI3k inhibitor. Anticancer agent 137 has broad-spectrum anticancer activity. Anticancer agent 137 induces G2/M cell cycle arrest and apoptosis. Anticancer agent 137 increases cleaved PARP, caspase 3, and 7. Anticancer agent 137 can be used in research of cancer[1].
CAS Number
[9007-83-4]
UNSPSC
12352005
Target
Apoptosis; Caspase; PARP; PI3K
Type
Reference compound
Related Pathways
Apoptosis; Cell Cycle/DNA Damage; Epigenetics; PI3K/Akt/mTOR
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/anticancer-agent-137.html
Solubility
10 mM in DMSO
Smiles
COC1=C(C(OC)=CC2=C1CCC(O2)C3=CC=CC(C(NC4=CC=C(C=C4)OC)=O)=C3)OC
Molecular Formula
C26H27NO6
Molecular Weight
449.50
References & Citations
[1]Hassan AHE, et, al. Scaffold hopping of N-benzyl-3,4,5-trimethoxyaniline: 5,6,7-Trimethoxyflavan derivatives as novel potential anticancer agents modulating hippo signaling pathway. Eur J Med Chem. 2023 Aug 5;256:115421.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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