Anticancer agent 137

• UNSPSC Description:

  Anticancer agent 137 (8q) is a potent PI3k inhibitor. Anticancer agent 137 has broad-spectrum anticancer activity. Anticancer agent 137 induces G2/M cell cycle arrest and apoptosis. Anticancer agent 137 increases cleaved PARP, caspase 3, and 7. Anticancer agent 137 can be used in research of cancer[1].

• Target Antigen:

  Apoptosis; Caspase; PARP; PI3K

• Type:

  Reference compound

• Related Pathways:

  Apoptosis;Cell Cycle/DNA Damage;Epigenetics;PI3K/Akt/mTOR

• Applications:

  Cancer-Kinase/protease

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/anticancer-agent-137.html

• Solubility:

  10 mM in DMSO

• Smiles:

  COC1=C(C(OC)=CC2=C1CCC(O2)C3=CC=CC(C(NC4=CC=C(C=C4)OC)=O)=C3)OC

• Molecular Weight:

  449.50

• References & Citations:

  [1]Hassan AHE, et, al. Scaffold hopping of N-benzyl-3,4,5-trimethoxyaniline: 5,6,7-Trimethoxyflavan derivatives as novel potential anticancer agents modulating hippo signaling pathway. Eur J Med Chem. 2023 Aug 5;256:115421.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  9007-83-4