CFL-137

CAT: 0804-HY-W016889-01Size: 25 gDry Ice: NoHazardous: No
CAT#:0804-HY-W016889-01Size:25 g
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
CFL-137 is a potent KRasG12C inhibitor. CFL-137 shows an antiproliferative effect. CFL-137 shows anticancer activity. CFL-137 has the potential for the research of lung cancer[1].
CAS Number
[708-06-5]
UNSPSC
12352005
Hazard Statement
H410
Target
Ras
Type
Reference compound
Related Pathways
GPCR/G Protein; MAPK/ERK Pathway
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/cfl-137.html
Purity
99.92
Solubility
DMSO : ≥ 100 mg/mL
Smiles
O=CC1=C2C=CC=CC2=CC=C1O
Molecular Formula
C11H8O2
Molecular Weight
172.18
Precautions
H410
References & Citations
[1]Orgován Z, et al. Covalent fragment mapping of KRasG12C revealed novel chemotypes with in vivo potency. Eur J Med Chem. 2023 Mar 15;250:115212.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, stored under nitrogen)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
K-Ras

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