Products for Research Use Only
RegisterLogin

Fumaric acid-13C2

CAT: 0804-HY-W015883S1-01Size: 1 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-W015883S1-01Size:1 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Fumaric acid-13C2 is the 13C-labeled Fumaric acid. Fumaric acid is an unsaturated dicarbonic acid, an intermediate product of the citric acid cycle that provides intracellular energy in the form of ATP. Fumaric acid exerts anti-inflammatory effects by inhibiting the NF-κB signaling pathway dependent on p38 MAPK. Fumaric acid can be used in the study of pregnancy-induced hypertension[1][2][3].
CAS Number
96503-56-9
UNSPSC
12352211
Hazard Statement
H319
Target
Endogenous Metabolite; Isotope-Labeled Compounds; NF-κB; p38 MAPK
Related Pathways
MAPK/ERK Pathway; Metabolic Enzyme/Protease; NF-κB; Others
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease; Inflammation/Immunology; Cardiovascular Disease
Purity
99.9
Smiles
O=[13C](O)/C=C/[13C](O)=O
Molecular Formula
C2 13C2H4O4
Molecular Weight
118.06
Precautions
H319
References & Citations
[1]Whelan DT, et al. Fumaric aciduria: a new organic aciduria, associated with mental retardation and speech impairment. Clin Chim Acta. 1983 Aug 31;132 (3) :301-8. |[2]Roh KB, et al. Fumaric acid attenuates the eotaxin-1 expression in TNF-α-stimulated fibroblasts by suppressing p38 MAPK-dependent NF-κB signaling. Food Chem Toxicol. 2013 Aug;58:423-31.|[3]Zhou Y, et al. Fumaric acid and succinic acid treat gestational hypertension by downregulating the expression of KCNMB1 and TET1. Exp Ther Med. 2021 Oct;22 (4) :1072.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported

Related Products

CatalogName
HY-W015883ASFumaric acid2,3-13C2 (disodium)
HY-W015883S-01Fumaric acid-13C4
HY-W015883-01Fumaric acid
HY-W015883S4-01Fumaric acid-d4
HY-W015883S3-01Fumaric acid-d2
HY-157257Trimethoprim fumaric acid
HY-W015883R-01Fumaric acid (Standard)
HY-W015883A-01Fumaric acid (disodium)
HY-W015883ARFumaric acid (disodium) (Standard)
HY-W778203Glycolic acid-13C2

Alternative Products

CatalogName
OR1076465Fumaric acid-13C2
sc-496745Fumaric acid-1,4-13C2
FF23617-01Fumaric acid

Popular Products