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AMG-780

CAT: 0804-HY-P991663Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-P991663Size:1 Each
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
AMG-780 is a fully human IgG2 antibody that targets angiopoietin 1 (Ang1) (IC50 = 4.5 nM) and angiopoietin 2 (Ang2) (IC50 = 0.06 nM) . AMG-780 inhibits tumor growth in the Colo205 xenograft mouse model by inhibiting both Ang1 and Ang2. AMG-780 is indicated for the research of cancers such as colon cancer[1][2].
UNSPSC
12352100
Target
Tie
Related Pathways
Protein Tyrosine Kinase/RTK
Field of Research
Cancer
References & Citations
[1]James V. Bready, et al. Abstract 1022: Development and preclinical testing of AMG 780, a fully human antibody targeting angiopoietin 1 (Ang1) and angiopoietin 2 (Ang2) . Cancer Res 1 October 2014; 74 (19_Supplement) : 1022. |[2]James V. Bready, et al. Abstract 1022: Development and preclinical testing of AMG 780, a fully human antibody targeting angiopoietin 1 (Ang1) and angiopoietin 2 (Ang2) . Cancer Res 1 October 2014; 74 (19_Supplement) : 1022.
Shipping Conditions
Room temperature
Scientific Category
Inhibitory Antibodies
Clinical Information
No Development Reported

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