LP17 (human)

• Description :

  LP17 (human) is a TREM1 antagonist peptide with anti-inflammatory and anti-cancer effects[1].

• CAS Number :

  [887973-05-9]

• UNSPSC :

  12352209

• Target :

  TREM receptor

• Related Pathways :

  Immunology/Inflammation

• Applications :

  COVID-19-immunoregulation

• Field of Research :

  Cancer; Inflammation/Immunology

• Purity :

  90.14

• Smiles :

  O=C(N1[C@@H](CCC1)C(O)=O)[C@H]2N(CCC2)C([C@H](CCC(N)=O)NC([C@@H](NC([C@H]([C@@H](C)CC)NC([C@H](C(C)C)NC([C@H](CS)NC([C@H](CCC(N)=O)NC([C@@H](NC([C@H](CC(C)C)NC(CNC([C@H](CO)NC([C@H](CC(O)=O)NC([C@H](CCC(O)=O)NC([C@H](C(C)C)NC([C@H](CCC(N)=O)NC([C@@H](N)CC(C)C)=O)=O)=O)=O)=O)=O)=O)=O)CC3=CC=C(C=C3)O)=O)=O)=O)=O)=O)CC4=CC=C(C=C4)O)=O)=O

• Molecular Formula :

  C88H134N20O28S

• Molecular Weight :

  1952.19

• References & Citations :

  [1]Roh SA, et al. SLAMF7 and TREM1 Mediate Immunogenic Cell Death in Colorectal Cancer Cells: Focus on Microsatellite Stability. Anticancer Res. 2021 Nov;41 (11) :5431-5444.

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  -80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)

• Scientific Category :

  Peptides

• Clinical Information :

  No Development Reported