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LP117

CAT: 0804-HY-U00438Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-U00438Size:1 Each
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Description
LP117 is a novel and potent inhibitor of 5-Lipoxygenase (5-LO) product synthesis with an IC50 of 1.1 μM.
CAS Number
1056468-55-3
UNSPSC
12352005
Target
Lipoxygenase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/LP117.html
Solubility
10 mM in DMSO
Smiles
CCCCC(SC1=NC(NC2=CC=C3N=CC=CC3=C2)=CC(Cl)=N1)C(OCC)=O
Molecular Formula
C21H23ClN4O2S
Molecular Weight
430.95
References & Citations
[1]Werz O, et al. Novel and potent inhibitors of 5-lipoxygenase product synthesis based on the structure of pirinixic acid. J Med Chem. 2008 Sep 11;51 (17) :5449-53.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
5-LOX

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