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LIH383

CAT: 0804-HY-P10333-01Size: 500 µgDry Ice: NoHazardous: No
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CAT#:0804-HY-P10333-01Size:500 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
LIH383 is an agonist of ACKR3 (CXCR7) (EC50=0.61 nM) . LIH383 efficiently induces the recruitment of β-arrestin to ACKR3 but does not trigger typical G protein signaling[1].
CAS Number
2866266-58-0
UNSPSC
12352209
Target
CXCR
Type
Peptides
Related Pathways
GPCR/G Protein; Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/lih383.html
Solubility
10 mM in DMSO
Smiles
O=C(NCC(NCC(N[C@@H](CC1=CC=CC=C1)C(N[C@@H](CCSC)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCCCN)C(N)=O)=O)=O)=O)=O)=O)=O)[C@H](CC2=CC=CC=C2)N
Molecular Formula
C45H72N16O8S
Molecular Weight
997.22
References & Citations
[1]Meyrath M, et al. The atypical chemokine receptor ACKR3/CXCR7 is a broad-spectrum scavenger for opioid peptides. Nat Commun. 2020 Jun 19;11 (1) :3033.
Shipping Conditions
Room temperature
Scientific Category
Peptides
Clinical Information
No Development Reported

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