(-) -Securinine (nitrate)

CAT: 0804-HY-N2079ASize: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-N2079ASize:1 Each
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Description
(-) -Securinine (nitrate) is plant-derived alkaloid and also a GABAA receptor antagonist[1][2].
CAS Number
[7104-26-9]
UNSPSC
12352005
Target
GABA Receptor
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Field of Research
Cancer; Neurological Disease
Smiles
O=C(O1)C=C2[C@@]13[C@](CCCC4)([H])N4[C@](C3)([H])C=C2.O[N+]([O-])=O
Molecular Formula
C13H16N2O5
Molecular Weight
280.28
References & Citations
[1]Stefanowicz-Hajduk J, et al. Securinine from Phyllanthus glaucus Induces Cell Cycle Arrest and Apoptosis in Human Cervical Cancer HeLa Cells. PLoS One. 2016 Oct 28;11 (10) :e0165372. |[2]Kalpana Gupta, et al. Securinine, a Myeloid Differentiation Agent with Therapeutic Potential for AML. PLoS One. 2011; 6 (6) : e21203.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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