TAN-1030A

• Description:

  TAN-1030A is an indolocarbazole alkaloid with macrophage-activating properties. TAN-1030A induces spreading of a murine macrophage cell line, Mm 1, and augmentes the phagocytic activity, Fc gamma receptor expression and β-glucuronidase activity of murine macrophage cell lines, Mm 1 and J774A.1. TAN-1030A can activate macrophage functions in mice[1].

• UNSPSC:

  12352005

• Target:

  β-glucuronidase

• Related Pathways:

  Metabolic Enzyme/Protease

• Field of Research:

  Inflammation/Immunology

• Purity:

  95.04

• Solubility:

  DMSO : 3.33 mg/mL (ultrasonic; warming; heat to 60°C)

• Smiles:

  C[C@]12N3C4=C(C5=CC=CC=C53)C(CNC6=O)=C6C7=C4N([C@](C/C([C@H]2OC)=N/O)([H])O1)C8=CC=CC=C78

• Molecular Formula:

  C27H22N4O4

• Molecular Weight:

  466.49

• References & Citations:

  [1]Tanida S, et al. TAN-999 and TAN-1030A, new indolocarbazole alkaloids with macrophage-activating properties. J Antibiot (Tokyo) . 1989 Nov;42 (11) :1619-30.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category:

  Natural Products

• Clinical Information:

  No Development Reported

• CAS Number:

  126221-76-9