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Thioflavin T (solution)

CAT: 0804-HY-DY1049-01Size: 1 mLDry Ice: NoHazardous: No
CAT#:0804-HY-DY1049-01Size:1 mL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Thioflavin T (solution) is a cationic Benzothiazole dye that shows enhanced fluorescence upon binding to amyloid in tissue sections. Excitation max.: ~385 nm (free) ; ~450 nm (bound) ; Emission max.: ~445 nm (free) ; ~485 nm (bound) [1][2][3].Solvent and Concentration: Sterile water: 10 mM
CAS Number
[2390-54-7]
Target
Amyloid-β
Related Pathways
Neuronal Signaling
Applications
Neuroscience-Neurodegeneration
Field of Research
Others
Smiles
CC1=CC=C2[N+](C)=C(C3=CC=C(N(C)C)C=C3)SC2=C1.[Cl-]
Molecular Formula
C17H19ClN2S
Molecular Weight
318.86
References & Citations
[1]Nakano H, et al. Globular-shaped Aβ oligomers have diverse mechanisms for promoting Aβ aggregations with the facilitation of fibril elongation. Neurobiol Dis. 2025 Feb;205:106775.|[2]Muramatsu D, et al. ALZ-801 prevents amyloid β-protein assembly and reduces cytotoxicity: A preclinical experimental study. FASEB J. 2025 Feb 15;39 (3) :e70382. |[3]Khurana R, et al. Mechanism of thioflavin T binding to amyloid fibrils. J Struct Biol. 2005 Sep;151 (3) :229-38.
Shipping Conditions
Room temperature
Scientific Category
Dye Reagents
Clinical Information
No Development Reported

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