Filipin complex (solution)

• Description :

  Filipin complex (solution) is a potent polyene macrolide antifungal antibiotic. Filipin complex inserts into membranes and sequester cholesterol into complexes and inhibits PRRSV entry. The Filipin complex consists of about 75.8% Filipin III (HY-N6718), 10.8% Filipin IV, 9.1% Filipin II, and 1.2% Filipin I (Ex/Em = 380/430 nm) [1][2][3].Solvent and concentration: DMSO: 5 mg/mL

• UNSPSC :

  12352211

• Target :

  Antibiotic; Fungal

• Related Pathways :

  Anti-infection

• Field of Research :

  Infection

• Smiles :

  [Filipincomplex(solution)]

• References & Citations :

  [1]Malcolm E. Bergy et al. Filipin complex. Biochemistry, 1968, 7, 2, 653-659.|[2]Houdai T, et al. Membrane-permeabilizing activities of amphidinol 3, polyene-polyhydroxy antifungal from a marine dinoflagellate. Biochim Biophys Acta. 2004 Nov 17;1667 (1) :91-100.|[3]Huang L, et al. Role of lipid rafts in porcine reproductive and respiratory syndrome virus infection in MARC-145 cells. Biochem Biophys Res Commun. 2011 Oct 28;414 (3) :545-50.|[4]Huang S, et al. Chimeric cerebral organoids reveal the essentials of neuronal and astrocytic APOE4 for Alzheimer's tau pathology. Signal Transduct Target Ther. 2022 Jun 13;7 (1) :176.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Dye Reagents

• Clinical Information :

  No Development Reported

• CAS Number :

  [11078-21-0]