NFC nitro probe 1

• Description:

  NFC nitro probe 1 (compound 18) is an NFC termed probe for Mtb detection. NFC nitro probe 1 (compound 18) shows high potency for R-Mtb and NR-Mtb[1][2].

• UNSPSC:

  12171500

• Target:

  Bacterial

• Related Pathways:

  Anti-infection

• Field of Research:

  Infection; Inflammation/Immunology

• Smiles:

  CC1(C)OC2=C3C(OC(C=C3CCC)=O)=C4C(OC([N+]([O-])=O)=C4)=C2CC1

• Molecular Formula:

  C19H19NO6

• Molecular Weight:

  357.36

• References & Citations:

  [1]Ana Negri, et al. Identification of a Mycothiol-Dependent Nitroreductase from Mycobacterium tuberculosis. ACS Infect Dis. 2018 May 11;4 (5) :771-787.|[2]Purong Zheng, et al. Synthetic calanolides with bactericidal activity against replicating and nonreplicating Mycobacterium tuberculosis. J Med Chem. 2014 May 8;57 (9) :3755-72.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Dye Reagents

• Clinical Information:

  No Development Reported

• CAS Number:

  [1604838-69-8]