Products for Research Use Only

AZ7550 Mesylate (Standard)

CAT: 0804-HY-B0794BR-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-B0794BR-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
AZ7550 Mesylate (Standard) is the analytical standard of AZ7550 Mesylate. This product is intended for research and analytical applications. AZ7550 Mesylate is an active metabolite of AZD9291 and inhibits the activity of IGF1R with an IC50 of 1.6 μM.
CAS Number
2319837-99-3
Product Name Alternative
AZ7550 trimesylate salt (Standard)
UNSPSC
12352005
Target
Drug Metabolite; EGFR; IGF-1R; Reference Standards
Related Pathways
JAK/STAT Signaling; Metabolic Enzyme/Protease; Others; Protein Tyrosine Kinase/RTK
Field of Research
Cancer; Endocrinology
Smiles
CN1C=C(C2=NC(NC3=CC(NC(C=C)=O)=C(N(CCNC)C)C=C3OC)=NC=C2)C4=CC=CC=C41.O=S(O)(C)=O.O=S(O)(C)=O.O=S(O)(C)=O
Molecular Formula
C30H43N7O11S3
Molecular Weight
773.90
References & Citations
[1]Finlay MR, et al. Discovery of a potent and selective EGFR inhibitor (AZD9291) of both sensitizing and T790M resistance mutations that spares the wild type form of the receptor. J Med Chem. 2014 Oct 23;57 (20) :8249-67.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards