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Bromocriptine (mesylate) (Standard)

CAT: 0804-HY-12705AR-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-12705AR-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Bromocriptine (mesylate) (Standard) is the analytical standard of Bromocriptine (mesylate) . This product is intended for research and analytical applications. Bromocriptine mesylate is a potent dopamine D2/D3 receptor agonist, which binds D2 dopamine receptor with pKi of 8.05±0.2.
CAS Number
22260-51-1
Product Name Alternative
CB-154 (Standard)
UNSPSC
12352005
Target
Autophagy; Dopamine Receptor; Reference Standards
Type
Reference compound
Related Pathways
Autophagy; GPCR/G Protein; Neuronal Signaling; Others
Field of Research
Neurological Disease; Cancer
Assay Protocol
https://www.medchemexpress.com/bromocriptine-mesylate-standard.html
Smiles
[H][C@@]12CC3=C(Br)NC4=CC=CC(C1=C[C@@H](C(N[C@@]5(C(C)C)C(N6[C@@H](CC(C)C)C(N7CCC[C@]7([C@]6(O)O5)[H])=O)=O)=O)CN2C)=C43.OS(=O)(C)=O
Molecular Formula
C33H44BrN5O8S
Molecular Weight
750.70
References & Citations
[1]Gardner B, et al. Agonist action at D2 (long) dopamine receptors: ligand binding and functional assays. Br J Pharmacol. 1998 Jul;124 (5) :978-84.|[2]Renodon A, et al. Bromocriptine is a strong inhibitor of brain nitric oxide synthase: possible consequences for the origin of its therapeutic effects.FEBS Lett. 1997 Apr 7;406 (1-2) :33-6.|[3]Wynalda MA, et al. Assessment of potential interactions between dopamine receptor agonists and various human cytochrome P450 enzymes using a simple in vitro inhibition screen. Drug Metab Dispos. 1997 Oct;25 (10) :1211-4.|[4]Rana DG, et al. Dopamine mediated antidepressant effect of Mucuna pruriens seeds in various experimental models of depression. Ayu. 2014 Jan;35 (1) :90-7.|[5]Dieb W, et al. Nigrostriatal dopaminergic depletion increases static orofacial allodynia. J Headache Pain. 2016;17:11.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards

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0427/50Bromocriptine mesylate
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