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Tofacitinib-13C, d3

CAT: 0804-HY-40354S2Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-40354S2Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Tofacitinib-13C, d3 (Tasocitinib-13C, d3) is 13C labeled Tofacitinib. Tofacitinib is an orally available JAK3/2/1 inhibitor with IC50s of 1, 20, and 112 nM, respectively.
Product Name Alternative
Tasocitinib-13C, d3; CP-690550-13C, d3
UNSPSC
12352005
Target
Isotope-Labeled Compounds
Related Pathways
Others
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology; Cancer
Smiles
C[C@H]1[C@H](CN(CC1)C(CC#N)=O)N(C2=C3C=CNC3=NC=N2)[13C]([2H])([2H])[2H]
Molecular Formula
C15 13CH17D3N6O
Molecular Weight
316.38
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216.
Shipping Conditions
Room temperature
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported

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