Tofacitinib-13C

• Description:

  Tofacitinib-13C (Tasocitinib-13C) is 13C labeled Tofacitinib. Tofacitinib is an orally available JAK3/2/1 inhibitor with IC50s of 1, 20, and 112 nM, respectively.

• Product Name Alternative:

  Tasocitinib-13C; CP-690550-13C

• UNSPSC:

  12352005

• Target:

  Isotope-Labeled Compounds

• Related Pathways:

  Others

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Inflammation/Immunology; Cancer

• Smiles:

  C[C@H]1[C@@H] (N (C) C2=C3C=CNC3=NC=N2) CN (C (C[13C]#N) =O) CC1

• Molecular Formula:

  C15 13CH20N6O

• Molecular Weight:

  313.36

• References & Citations:

  [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Isotope-Labeled Compounds

• Clinical Information:

  No Development Reported