Tofacitinib-d3

CAT: 0804-HY-40354S5Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-40354S5Size:1 Each
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Tofacitinib-d3 (Tasocitinib-d3) is deuterium labeled Tofacitinib. Tofacitinib is an orally available JAK3/2/1 inhibitor with IC50s of 1, 20, and 112 nM, respectively.
Product Name Alternative
Tasocitinib-d3; CP-690550-d3
UNSPSC
12352005
Target
Isotope-Labeled Compounds
Related Pathways
Others
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology; Cancer
Smiles
O=C(N1C[C@@H]([C@@H](CC1)C)N(C([2H])([2H])[2H])C2=C3C(NC=C3)=NC=N2)CC#N
Molecular Formula
C16H17D3N6O
Molecular Weight
315.39
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216.
Shipping Conditions
Room temperature
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported

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