Tofacitinib-d3

• Description:

  Tofacitinib-d3 (Tasocitinib-d3) is deuterium labeled Tofacitinib. Tofacitinib is an orally available JAK3/2/1 inhibitor with IC50s of 1, 20, and 112 nM, respectively.

• Product Name Alternative:

  Tasocitinib-d3; CP-690550-d3

• UNSPSC:

  12352005

• Target:

  Isotope-Labeled Compounds

• Related Pathways:

  Others

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Inflammation/Immunology; Cancer

• Smiles:

  O=C (N1C[C@@H] ([C@@H] (CC1) C) N (C ([2H]) ([2H]) [2H]) C2=C3C (NC=C3) =NC=N2) CC#N

• Molecular Formula:

  C16H17D3N6O

• Molecular Weight:

  315.39

• References & Citations:

  [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Isotope-Labeled Compounds

• Clinical Information:

  No Development Reported