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ANA-975

CAT: 0804-HY-19844Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-19844Size:1 Each
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Description
ANA975, 5-amino-3-β -D-ribofuranosyl-3H-thiazolo[4,5-d]pyrimidin-2-one derivative, is an oral prodrug of the TLR-7 agonist Isatoribine (HY-13655A) . ANA975 is converted to Isatoribine via a combined mechanism of hydrolysis by esterases and oxidation by aldehyde oxidase. ANA975 can be used in the research of hepatitis C virus infection[1].
CAS Number
[847453-47-8]
UNSPSC
12352005
Target
Aldehyde Oxidase (AO) ; Drug Derivative
Related Pathways
Metabolic Enzyme/Protease; Others
Field of Research
Infection
Smiles
O=C1SC2=CN=C(N)N=C2N1[C@H]3[C@@H]([C@@H]([C@@H](CO)O3)OC(C)=O)OC(C)=O
Molecular Formula
C14H16N4O7S
Molecular Weight
384.36
References & Citations
[1]Xiang AX, et al. Discovery of ANA975: an oral prodrug of the TLR-7 agonist isatoribine. Nucleosides Nucleotides Nucleic Acids. 2007;26 (6-7) :635-40.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 1

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