BAM-1110

• Description:

  BAM-1110 is a dopamine receptor agonist. BAM-1110 exhibits dose-dependent antiparkinsonian activity in MPTP (HY-W114750) -treated monkey models of Parkinson's disease. BAM-1110 has minimal side effects and can be used for the research of Parkinson's disease and other neurological disorders[1].

• UNSPSC:

  12352005

• Target:

  Dopamine Receptor

• Related Pathways:

  GPCR/G Protein; Neuronal Signaling

• Field of Research:

  Neurological Disease

• Smiles:

  OC(/C=C\C(O)=O)=O.CN1[C@@]2([H])[C@@](C[C@H](C1)CN3C=NC=N3)([H])C4=CC=CC5=C4C(C2)=CN5.[x]

• Molecular Formula:

  C18H21N5.xC4H4O4

• Molecular Weight:

  307.39 (free base)

• References & Citations:

  [1]Kuno S, et al. Antiparkinsonian effects of BAM-1110, a novel ergoline derivative, in MPTP-treated cynomolgus monkeys. Clin Neuropharmacol. 1998 Jan-Feb;21 (1) :35-40.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  Phase 2

• CAS Number:

  [155210-57-4]