BAM7

• Description:

  BAM7 is a direct and selective activator of proapoptotic BAX with an IC50 of 3.3 μM.

• UNSPSC:

  12352005

• Hazard Statement:

  H302

• Target:

  Bcl-2 Family

• Type:

  Reference compound

• Related Pathways:

  Apoptosis

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/bam7.html

• Purity:

  98.53

• Solubility:

  DMSO : 5 mg/mL (ultrasonic)

• Smiles:

  CCOC1=CC=CC=C1N/N=C2C(C)=NN(C3=NC(C4=CC=CC=C4)=CS3)C\2=O

• Molecular Formula:

  C21H19N5O2S

• Molecular Weight:

  405.47

• Precautions:

  H302

• References & Citations:

  [1]Gavathiotis E, et al. Direct and selective small-molecule activation of proapoptotic BAX. Nat Chem Biol. 2012 Jul;8 (7) :639-45.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• Isoform:

  Bax

• CAS Number:

  331244-89-4