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FK 584

CAT: 0804-HY-19228Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-19228Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
FK 584 is a potent detrusor muscle contraction inhibitor. FK 584 possesses potent antimuscarinic activity and weak calcium channel blocking activity. FK 584 has demonstrated potent detrusor muscle inhibitory activity in various experimental models with a manageable risk of mydriasis. FK 584 can be used to study overactive bladder (OAB) .
CAS Number
138951-54-9
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
Calcium Channel; mAChR
Related Pathways
GPCR/G Protein; Membrane Transporter/Ion Channel; Neuronal Signaling
Field of Research
Metabolic Disease; Neurological Disease
Smiles
CC(C)(C)N[C@H]1CC(C2=CC=CC=C2)(C3=CC=CC=C3)C=C1
Molecular Formula
C21H25N
Molecular Weight
291.43
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
References & Citations
[1]Taniguchi K, et al. Agents for the treatment of overactive detrusor. VIII. Synthesis and pharmacological properties of 4,4-diphenyl-2-cycloalkenylamines including FK584 and 3,3- or 4,4-diphenylcycloalkylamines. Chem Pharm Bull (Tokyo) . 1995 Jan;43 (1) :71-7.
Shipping Conditions
Room temperature
Scientific Category
Reference compound2
Clinical Information
Phase 2

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