MOR agonist-5

• Description:

  MOR agonist-5 is a selective and potent mu-opioid receptor (MOR) agonist with an EC50 of 0.25 nM. MOR agonist-5 shows an EC50 of 10 nM for DOR and >10000 nM for KOR and NOR. MOR agonist-5 exerts significant antinociceptive activity. MOR agonist-5 can be used for the research of pain[1].

• UNSPSC:

  12352005

• Target:

  Opioid Receptor

• Related Pathways:

  GPCR/G Protein; Neuronal Signaling

• Field of Research:

  Neurological Disease

• Smiles:

  NC (C1=CC (N2[C@H]3CC[C@@H]2CN (CCCC4=CC=CC=C4) C3) =CC=C1) =O

• Molecular Formula:

  C22H27N3O

• Molecular Weight:

  349.47

• References & Citations:

  [1]Trivedi RR, et al. N- (3-Hydroxyphenyl) -3,8-diazabicyclooctanes as opioid receptors probes. 1. Investigation of the phenolic hydroxyl group. Eur J Med Chem. 2025;298:117991.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• Isoform:

  NOP Receptor/ORL1; δ Opioid Receptor/DOR; κ Opioid Receptor/KOR; μ Opioid Receptor/MOR

• CAS Number:

  3085132-31-3